In case anyone else comes across this, in Device Manager, I did Show Hidden Devices (under View menu) and in other devices, there were 4 or 5 instances of all of the Targus devices showing - even after running clean up etc. Deleted all of these, re-ran clean up just in case, rebooted, plugged in docking station, ran Windows Update, and all's back to normal. So, looks like those old devices were confusing things.
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